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Nonetheless, further research is warranted to clarify potential subgroup-specific effects and account for confounding factors such as nutritional status, comorbid metabolic disorders, and heterogeneity among depression subtypes

K/BxN serum transfer mice developed periosteal new bone formation and articular cartilage damage with cartilaginous metaplasia 29 days post-serum transfer (114)

One promising avenue is the utilization of plant-based remediation strategies, where certain plant species exhibit the ability to accumulate and detoxify heavy metals from the soil